American College Of Surgeons - Inspiring Quality: Highest Standards, Better Outcomes

Alliance/American College of Surgeons Clinical Research Program

The mission of the Alliance/American College of Surgeons Clinical Research Program (ACS CRP) is to reduce the impact of cancer by increasing knowledge and awareness of new evidence and practice standards; increasing the participation of community oncology surgeons in cancer research and cancer care activities; developing and implementing evidence-based practices in surgical oncology; and creating opportunities for meaningful health services research.


The program has four committees with unique goals and activities that work together to reach the program's overall research goals. These committees include:

The Principal Investigator and Director of the ACS CRP is Kelly Hunt MD, chair and professor, department of breast surgical oncology, division of surgery, the University of Texas MD Anderson Cancer Center.

The ACS CRP was created when the American College of Surgeons Oncology Group (ACOSOG), North Central Cancer Treatment Group (NCCTG), and Cancer and Leukemia Group B (CALGB) merged to form the Alliance for Clinical Trials in Oncology (Alliance) in 2012. The ACS CRP benefits from a close relationship with the American College of Surgeons (ACS) and the Commission on Cancer (CoC)—organizations that can help validate and disseminate research from the Alliance. Together these groups share responsibility for developing surgical standards for use in Alliance clinical trial protocols and CoC accreditation in addition to disseminating new evidence-based knowledge.

Get Involved

The Alliance and the ACS CRP offer many opportunities for surgeons involved in the care of cancer patients to get involved in the research and development of evidence-based practices in surgical oncology.

For more information, e-mail

COVID-19 & Cancer Studies

Given the emerging urgent need to better understand the impact of the COVID-19 pandemic on cancer care, numerous clinical studies have been developed by various organizations in addition to crowdsourcing efforts. Linked below is a succinct list of current ongoing studies compiled by the ACS CRP.

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Tumor Board Education

The first course of the Tumor Board Educational Series is now available. This 10-minute video will focus on the results and lessons learned from the ACOSOG Z1071 trial, which evaluated the accuracy of sentinel lymph node biopsy after neoadjuvant chemotherapy in clinically node positive breast cancer patients.

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Enrollment Resources

Are you a surgeon interested in participating in clinical trials but are unsure how to get started? New resources developed through the ACS CRP have been released to help guide surgeons through the administrative and regulatory requirements needed to participate in clinical trials.

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2020 CoC Standards

The Commission on Cancer 2020 Standards include six new Operative Standards, developed from standards described in Operative Standards for Cancer Surgery Volumes I & II. Learn how to incorporate these standards into your practice.

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ACS CRP Articles

The Bulletin of the American College of Surgeons is the College’s monthly member magazine, containing articles on topics that affect surgical practice and the surgical profession. Each month, the ACS CRP publishes an article in the Bulletin related to clinical trials in cancer.

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Operative Standards

The Operative Standards for Cancer Surgery, Volumes 1 & 2 offer concrete, evidence-based recommendations on cancer surgery techniques critical to achieving optimal outcomes. Available for purchase in both print and electronic formats, including individual disease sites, and for Kindle.

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